Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFKB1 All Species: 21.21
Human Site: Y349 Identified Species: 42.42
UniProt: P19838 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P19838 NP_003989.2 968 105356 Y349 S E P K P F L Y Y P E I K D K
Chimpanzee Pan troglodytes XP_001168657 976 106346 Y357 S E P K P F L Y Y P E I K D K
Rhesus Macaque Macaca mulatta XP_001109228 968 105518 Y349 S E P K P F L Y Y P E I K D K
Dog Lupus familis XP_862878 904 96875 V335 L V E D K E E V Q R K R R K A
Cat Felis silvestris
Mouse Mus musculus P25799 971 105623 Y347 S E P K P F L Y Y P E I K D K
Rat Rattus norvegicus Q63369 522 56535
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514381 266 29283
Chicken Gallus gallus Q04861 984 108151 Y354 S E P K P F L Y Y P E I K D K
Frog Xenopus laevis O73630 958 105836 Y331 S D S K Q F T Y Y P L E Q D K
Zebra Danio Brachydanio rerio NP_001001840 902 98760 D332 L K R K K G G D C S E P K Q F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P15330 999 111533 Q363 L D A K R E V Q P P T I E V I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999819 1125 124026 F358 S D P K P F T F H P Q V P D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.7 42.9 N.A. 86.7 47.3 N.A. 26 71.6 39.3 40.1 N.A. 22.8 N.A. N.A. 35.7
Protein Similarity: 100 99.1 99.1 56.8 N.A. 91.8 50.3 N.A. 27 82.7 56.2 54.4 N.A. 38.7 N.A. N.A. 52
P-Site Identity: 100 100 100 0 N.A. 100 0 N.A. 0 100 53.3 20 N.A. 20 N.A. N.A. 46.6
P-Site Similarity: 100 100 100 13.3 N.A. 100 0 N.A. 0 100 66.6 26.6 N.A. 40 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 25 0 9 0 0 0 9 0 0 0 0 0 59 0 % D
% Glu: 0 42 9 0 0 17 9 0 0 0 50 9 9 0 0 % E
% Phe: 0 0 0 0 0 59 0 9 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 9 % I
% Lys: 0 9 0 75 17 0 0 0 0 0 9 0 50 9 50 % K
% Leu: 25 0 0 0 0 0 42 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 50 0 50 0 0 0 9 67 0 9 9 0 0 % P
% Gln: 0 0 0 0 9 0 0 9 9 0 9 0 9 9 0 % Q
% Arg: 0 0 9 0 9 0 0 0 0 9 0 9 9 0 9 % R
% Ser: 59 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 17 0 0 0 9 0 0 0 0 % T
% Val: 0 9 0 0 0 0 9 9 0 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 50 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _